Zyban is an antidepressant medication. Zyban is used to help people stop smoking by reducing cravings and other withdrawal effects.


  • Effective smoking cure
  • Treats seasonal depression
  • It contributes to the production of the hormone of happiness – dopamine
  • Promotes weight loss
  • Reduces appetite
  • Therapy for ADD (attention deficit disorder) and hyperactivity
  • In the market since 1997
  • Affordable cost
  • Over-the-counter drug
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  • Package: 60, 90 – pills

Zyban is an antidepressant medication. Zyban is used to treat major depressive disorder and seasonal affective disorder. Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects. Zyban may also be used for purposes not listed in this medication guide.

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Bupropion can be taken with or without food.
 Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time, which could increase side effects including seizures. 
If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the second week of treatment. Talk to your doctor if you are having trouble quitting after you have used Zyban for at least 7 weeks.
Using nicotine with Zyban may raise your blood pressure and your doctor may want to check your blood pressure regularly. Do not smoke at any time if you are using a nicotine product along with Zyban. Too much nicotine can cause serious side effects.
 Do not stop taking bupropion without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly. This medication can cause you to have a false positive drug screeningtest. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.

Active Ingredient: bupropion 150mg

Do not take bupropion if you have taken a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. You should not take bupropion if you have: 
epilepsy or a seizure disorder;
an eating disorder such as anorexia or bulimia;
if you are using a second form of bupropion; or
if you have suddenly stopped using alcohol or sedatives (such as Valium).
Bupropion may cause seizures, especially in people with certain medical conditions. Tell your doctor about all of your medical conditions.
To make sure you can safely take bupropion, tell your doctor if you have any of these other conditions:
a history of head injury, seizures, or brain or spinal cord tumor;
heart disease, high blood pressure, history of heart attack;
kidney or liver disease (especially cirrhosis); or
bipolar disorder (manic depression).

Frequently asked questions

From one cigarette you smoked, no one died except a horse. And what happens to the body over time, when smoking has become your constant companion and lifestyle, as a cure for stress and tension, and just as leisure time with friends during lunch break? Here are some facts about smoking and their effects:

  1. Smoking causes lung cancer in 90% of all cases.
  2. The smoker is several times more susceptible to the harmful effects of other harmful factors (nutrition, alcohol, ecology).
  3. It is very difficult for smokers to overcome this habit. A complete rejection of cigarettes, in most cases, occurs only after suffering a stroke, or myocardial infarction.
  4. The fact that nicotine reduces the risk of Alzheimer’s disease is a fable invented by tobacco tycoons.
  5. Many smokers find themselves quitting because of the myths about the complexity of this process. But, about 65% of former smokers say, if they knew it would be so easy, they would refuse cigarettes much earlier.
  6. 5 cigarettes contain the amount of nicotine that can kill a person.
  7. To add flavor to cigarettes, urea is added to the products.
  8. The composition of tobacco smoke includes more than 45 dangerous carcinogens.
  9. 1/2 of all children of the planet are passive smokers, which causes frequent cases of bronchial asthma in childhood.
  10. Living with a smoker, being exposed to constant passive smoking increases the risk of lung cancer by 23%, even among those who have never smoked.
  11. 10% of smokers die prematurely from oncological diseases caused by tobacco.
  12. Myocardial infarction in smokers is 8 times more common than in non-smokers.
  13. The cause of 1/4 of all household household fires is a non-extinguished cigarette.
  14. When inhaling tobacco smoke, nicotine reaches the brain in just 10 seconds.
  15. Every fifth dead person in the world dies precisely from smoking.
  16. More than 400,000 people die from smoking each year.
  17. In the world, 2 people die of lung cancer every minute.
  18. Actors who starred in commercials for famous Marlboro cigarettes died of lung cancer. After this, this brand is popularly called the “killer of cowboys.” Every third adult on the planet is nicotine dependent.
  19. Menthol flavored cigarettes have a very negative effect on the cardiovascular system, leading to impotence in a short period of smoking.
  20. In pairs where one or both of the partners are smoking, they will not be able to conceive a child. To conceive and give birth to a healthy baby, at least 4 years must pass after a complete rejection of cigarettes. During this period, the cells and tissues of the body can regenerate.

The main active component of the tablets is Buprio. This substance is an antidepressant, so initially it was used only for the treatment of psychological problems. To this end, since 1985 it was sold under the brand name Velbutrin. He helped fight depression, stress, anxiety, seasonal mood swings, hyperactivity and attention deficit disorder. In the USA, this is still a very popular medicine used in psychiatry.

The effect of the drug is felt after two weeks from the beginning of the reception, in some cases it happens later. The drug showed an excellent result when it was consumed for one year.

Bupropion is used to treat the symptoms of depression and seasonal affective disorder (SAD). With SAD, people have episodes of depression that occur in the fall and winter.

The drug is prescribed in the following cases: Treatment of nicotine addiction.

Therapy for obesity and erectile dysfunction. Elimination of serous affective disorders and neuropathic pain.

As an auxiliary component in the treatment of Crohn’s disease and psoriasis.

Therapy for ADD (attention deficit disorder) and hyperactivity.

The course of therapy should be at least seven weeks. In this case, the first 6 days should be taken once 150 mg of the drug, for this purpose use the appropriate number of tablets, which are of different dosages.

Starting from day 7, take 150 mg of the drug twice a day. Tablets are not recommended to be chewed and crushed, washed down with half a glass of water. In the second week of using the drug, you need to decide on the day when smoking is stopped, the dosage of the tablets is not changed after that, continue to take them in the same mode. The maximum single dosage of tablets is 450 mg, they are taken strictly once a day at the same time, preferably in the morning. In severe cases, the dosage is increased by 3 days of treatment or after 2 weeks by one hundred milligrams.

If a person has renal insufficiency, it is recommended to begin therapy with a minimum dosage of 150 mg per day, since the active substance has the ability to accumulate in the body.

With liver pathologies, the time between taking the drug should be increased, in this case, the tablets are taken once every 2 days at a dosage of 150 mg.

Initial dose: 150 mg orally once a day in the morning.

Maintenance dose: after at least 4 days, the dose may be increased to 100–150 mg twice a day. If after several weeks there is no adequate improvement, the dose can be increased to 200 mg twice a day.

Do not use this medication if you:

are allergic to bupropion or to any of the ingredients of the medication

are currently taking thioridazine (an antipsychotic medication) or has taken it in the past 2 weeks

are having abrupt withdrawal issues from alcohol, benzodiazepines (e.g., diazepam, clonazepam, lorazepam), or other sedatives (e.g., phenobarbital)

are taking another medication that contains bupropion (e.g., Wellbutrin® or Wellbutrin® XL)

have a seizure disorder or a history of seizures

have or have had an eating disorder (bulimia or anorexia nervosa)

have taken a monoamine oxidase inhibitor (MAO inhibitor; e.g., phenelzine, tranylcypromine) within the past 2 weeks

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to replenish the missed dose.

Drinking alcohol with bupropion may increase the risk of seizures. If you regularly drink alcohol, talk to your doctor before changing the amount you drink. Bupropion can also cause seizures in people who drink a lot of alcohol and then suddenly stop drinking when they start using the medicine.

Bupropion may impair your thinking or reactions. Be careful if you are driving or doing everything that requires your attention.

Smoker Reviews

William, 35 years old.

I have a small smoker experience, just a year. Therefore, I decided to abandon nicotine as soon as possible, until my health was too bad. Zyban has learned about the drug from a friend whom he helped quit smoking. He drank pills for a month and a half, and in fact lost the habit of cigarettes. If earlier every day I took out five to seven pieces from a pack, now I don’t want to make a single puff. What pleasantly surprised – did not torment “breaking”. I was not nervous at all, on the contrary, I was calm as never before. Hot temper, aggressiveness gone. I feel great, I began to sleep better and even slightly lost weight. Definitely I advise everyone to Zyban.

Helen, 40 years old.

On the description of the drug Zyban accidentally stumbled on the Internet. It has long been looking for a tool that helps to quit smoking quickly and without discomfort. It really helped, I completely gave up cigarettes after 10 days. Unfortunately, there were some minor side effects. I was drowsy, sometimes I felt overworked, but it all passed quickly. I think without Zyban I would have been harder to give up nicotine. Still, I smoked a long time, from the very students.

Jon, 51 years old.

Zyban – a great tool. I bought it at random, and not a bit sorry. I quit smoking after a month and a half, although I couldn’t cope with this addiction for years. As soon as stresses and mood swings began, I immediately grabbed hold of cigarettes, but now I am indifferent to tobacco. The main advantage of pills is that they calm the nerves. In addition, compared with sprays or nicotine gum, they do not cause aversion to taste. I will definitely recommend Zyban to everyone I know who also wants to part with cigarettes easily.

The drug is not used in pediatric practice. Children and adolescents have a higher risk of suicidal thoughts and behaviors.

Patients over the age of 65 are advised to adjust the dosage or reduce the frequency of taking the medicine. In this group of individuals, the likelihood of adverse reactions is increased.

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