Today, Wellbutrin (Bupropion), whose instructions are presented below, is the fourth most common drug used in the world to treat smoking dependence. Bobropion is used to help people quit smoking, reducing cravings and other cancellation effects.


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Wellbutrin (bupropion) is an antidepressant medication. It works in the brain to treat depression.
Wellbutrin is used to treat major depressive disorder and seasonal affective disorder. At least one brand of bupropion (Zyban) is used to help people stop smoking by reducing cravings and other withdrawal effects.
Wellbutrin may also be used for other purposes not listed in this medication guide.

Take Wellbutrin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Wellbutrin can be taken with or without food.
Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time, which could increase side effects including seizures.
Do not stop taking Wellbutrin without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly.
If you use the Wellbutrin extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.
Wellbutrin can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.

Active Ingredient: bupropion 300mg

Important safety information:

  • Wellbutrin may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Wellbutrin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Wellbutrin; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Wellbutrin may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you use a lot of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Wellbutrin.

  • If you already drink alcohol or use sedatives, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.

  • Do not take decongestants (eg, pseudoephedrine), stimulants, or diet pills while you are taking Wellbutrin without first checking with your doctor. They may increase your risk of seizures.

  • The risk of seizures may be greater if you take Wellbutrin in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Wellbutrin for longer than prescribed without checking with your doctor.

  • Children, teenagers, and young adults who take Wellbutrin may be at increased risk for suicidal thoughts or actions. Watch all patients who take Wellbutrin closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.

  • If you have trouble sleeping, you may be taking your dose too close to bedtime. Talk with your doctor about changing your dosing schedule.

  • Wellbutrin contains the same ingredients as Zyban, a medicine used to help stop smoking, and Aplenzin, another medication used to treat depression. Do not take Wellbutrin if you are also taking Zyban or Aplenzin. Discuss any questions or concerns with your doctor.

  • Use Wellbutrin with caution in the elderly; they may be more sensitive to its effects.

  • Wellbutrin should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Frequently asked questions

From one cigarette you smoked, no one died except a horse. And what happens to the body over time, when smoking has become your constant companion and lifestyle, as a cure for stress and tension, and just as leisure time with friends during lunch break? Here are some facts about smoking and their effects:

  1. Smoking causes lung cancer in 90% of all cases.
  2. The smoker is several times more susceptible to the harmful effects of other harmful factors (nutrition, alcohol, ecology).
  3. It is very difficult for smokers to overcome this habit. A complete rejection of cigarettes, in most cases, occurs only after suffering a stroke, or myocardial infarction.
  4. The fact that nicotine reduces the risk of Alzheimer’s disease is a fable invented by tobacco tycoons.
  5. Many smokers find themselves quitting because of the myths about the complexity of this process. But, about 65% of former smokers say, if they knew it would be so easy, they would refuse cigarettes much earlier.
  6. 5 cigarettes contain the amount of nicotine that can kill a person.
  7. To add flavor to cigarettes, urea is added to the products.
  8. The composition of tobacco smoke includes more than 45 dangerous carcinogens.
  9. 1/2 of all children of the planet are passive smokers, which causes frequent cases of bronchial asthma in childhood.
  10. Living with a smoker, being exposed to constant passive smoking increases the risk of lung cancer by 23%, even among those who have never smoked.
  11. 10% of smokers die prematurely from oncological diseases caused by tobacco.
  12. Myocardial infarction in smokers is 8 times more common than in non-smokers.
  13. The cause of 1/4 of all household household fires is a non-extinguished cigarette.
  14. When inhaling tobacco smoke, nicotine reaches the brain in just 10 seconds.
  15. Every fifth dead person in the world dies precisely from smoking.
  16. More than 400,000 people die from smoking each year.
  17. In the world, 2 people die of lung cancer every minute.
  18. Actors who starred in commercials for famous Marlboro cigarettes died of lung cancer. After this, this brand is popularly called the “killer of cowboys.” Every third adult on the planet is nicotine dependent.
  19. Menthol flavored cigarettes have a very negative effect on the cardiovascular system, leading to impotence in a short period of smoking.
  20. In pairs where one or both of the partners are smoking, they will not be able to conceive a child. To conceive and give birth to a healthy baby, at least 4 years must pass after a complete rejection of cigarettes. During this period, the cells and tissues of the body can regenerate.

Today, Bupropion, whose instructions are presented below, is the fourth most common drug used in the world to treat smoking dependence.

The effect of the drug is felt after two weeks from the beginning of the reception, in some cases it happens later. The drug showed an excellent result when it was consumed for one year.

Bupropion is used to treat the symptoms of depression and seasonal affective disorder (SAD). With SAD, people have episodes of depression that occur in the fall and winter.

The drug is prescribed in the following cases: Treatment of nicotine addiction.

Therapy for obesity and erectile dysfunction. Elimination of serous affective disorders and neuropathic pain.

As an auxiliary component in the treatment of Crohn’s disease and psoriasis.

Therapy for ADD (attention deficit disorder) and hyperactivity.

The course of therapy should be at least seven weeks. In this case, the first 6 days should be taken once 150 mg of the drug, for this purpose use the appropriate number of tablets, which are of different dosages.

Starting from day 7, take 150 mg of the drug twice a day. Tablets are not recommended to be chewed and crushed, washed down with half a glass of water. In the second week of using the drug, you need to decide on the day when smoking is stopped, the dosage of the tablets is not changed after that, continue to take them in the same mode. The maximum single dosage of tablets is 450 mg, they are taken strictly once a day at the same time, preferably in the morning. In severe cases, the dosage is increased by 3 days of treatment or after 2 weeks by one hundred milligrams.

If a person has renal insufficiency, it is recommended to begin therapy with a minimum dosage of 150 mg per day, since the active substance has the ability to accumulate in the body.

With liver pathologies, the time between taking the drug should be increased, in this case, the tablets are taken once every 2 days at a dosage of 150 mg.

Initial dose: 150 mg orally once a day in the morning.

Maintenance dose: after at least 4 days, the dose may be increased to 100–150 mg twice a day. If after several weeks there is no adequate improvement, the dose can be increased to 200 mg twice a day.

Do not use this medication if you:

are allergic to bupropion or to any of the ingredients of the medication

are currently taking thioridazine (an antipsychotic medication) or has taken it in the past 2 weeks

are having abrupt withdrawal issues from alcohol, benzodiazepines (e.g., diazepam, clonazepam, lorazepam), or other sedatives (e.g., phenobarbital)

are taking another medication that contains bupropion (e.g., Zyban® or Wellbutrin® XL)

have a seizure disorder or a history of seizures

have or have had an eating disorder (bulimia or anorexia nervosa)

have taken a monoamine oxidase inhibitor (MAO inhibitor; e.g., phenelzine, tranylcypromine) within the past 2 weeks

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to replenish the missed dose.

Drinking alcohol with bupropion may increase the risk of seizures. If you regularly drink alcohol, talk to your doctor before changing the amount you drink. Bupropion can also cause seizures in people who drink a lot of alcohol and then suddenly stop drinking when they start using the medicine.

Bupropion may impair your thinking or reactions. Be careful if you are driving or doing everything that requires your attention.

Basically, the drug “Bupropion” has positive reviews. Many patients noted the emergence of emotional lift and vigor, the desire to perform activities. Traction to smoking disappeared in the first week of taking the drug. Consumers say that this drug does not develop the so-called narcotic pleasure. This drug has a good therapeutic effect, so doctors often prescribe the drug to patients who are trying to get rid of nicotine addiction and suffering from depression.

The drug is not used in pediatric practice. Children and adolescents have a higher risk of suicidal thoughts and behaviors.

Patients over the age of 65 are advised to adjust the dosage or reduce the frequency of taking the medicine. In this group of individuals, the likelihood of adverse reactions is increased.

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